Product Description
| Reactivity: | H,M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Arginase1 rabbit polyclonal antibody |
Gene Name: | Arginase-1 |
Synonyms: | Arg1,Arg-1,Arginase 1,Liver-Type Arginase,Arginase, Type I Arginase,Arginase-1 |
Uniprot ID: | |
Immunogen: | Recombinant protein corresponding to Mouse Arginase-1 |
Isotype: | IgG |
Subcellular location: | Cytoplasm |
Predicted MW. | 35 kDa |
Observed MW. | 40 kDa |
Purity: | Affinity purification |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human,Mouse,Rat | 1: 1000-1: 10000 | liver |
IHC/IF | Human,Mouse,Rat | 1: 500-1: 1000 | liver |
Background
Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia .
Images
| Western blot analysis of Arginase 1 (GB11285) at dilution of 1: 10000 |
| Immunohistochemistry analysis of paraffin-embedded mouse liver using Arginase 1 GB11285 at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin-embedded rat liver using Arginase 1 GB11285 at dilution of 1: 1000 |
| Immunofluorescent analysis of paraformaldehyde-fixed mouse liver using Arginase 1 GB11285 at dilution of 1: 1000 |
| Immunofluorescent analysis of paraformaldehyde-fixed rat liver using Arginase 1 GB11285 at dilution of 1: 1000 |
Storage
| Storage | Store at -20 °C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
