Product Description
| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | APC. Ex:650nm. Em:660nm. |
| Gene Name: | ADAM metallopeptidase domain 10 |
| Gene Symbol: | ADAM10 |
| Synonyms: | RAK; kuz; AD10; AD18; MADM; CD156c; CDw156; HsT18717 |
| Gene ID: | 102 |
| UniProt ID: | O14672 |
| Immunogen: | Recombinant Protein corresponding to a sequence within amino acids 214-672 of human ADAM10 (NP_001101.1). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/ml |
| Buffer: | PBS with 0.09% Sodium azide,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-ADAM10 Antibody |
Background
Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. Alternate splicing results in multiple transcript variants encoding different proteins that may undergo similar processing.
Images
 | Flow cytometry: 1×10^6 SH-SY5Y cells (Low Expression,left) and A431 cells (right) were surface-stained with APC Rabbit anti-Human CD156c/ADAM10 mAb (A27129,5 μl/Test,orange line) or APC Rabbit IgG isotype control (A24173,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 A431 cells were surface-stained with APC Rabbit IgG isotype control (A24173,5 μl/Test,left) or APC Rabbit anti-Human CD156c/ADAM10 mAb (A27129,5 μl/Test,right). |
 | Flow cytometry: 1×10^6 Human PBMC were surface-stained with APC Rabbit anti-Human CD156c/ADAM10 mAb (A27129,5 μl/Test,orange line) or APC Rabbit IgG isotype control (A24173,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). Cells in the gate were used for analysis. |
| Flow cytometry: 1×10^6 Human PBMC were surface-stained with APC Rabbit IgG isotype control (A24173,5 μl/Test,left) or APC Rabbit anti-Human CD156c/ADAM10 mAb (A27129,5 μl/Test,right). |
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